Recent oral studies show that N4 Pharma has completed two in vivo studies demonstrating that when Nuvec® is loaded with OVA m-cherry DNA and encapsulated within an acid protective polymer it can be dosed orally.
In the first study, Nuvec® was formulated together with the OVA and the whole formulation was coated with the polymer as a capsule. In the second study the nanoparticles, once loaded with OVA, were individually encapsulated with the polymer, and administered via an oral gavage.
To see our proof of concept data contact us here.